CALCIFICATION AND OSSIFICATION

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چکیده

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Extraskeletal (Ectopic) Calcification and Ossification

A significant number and variety of disorders cause extraskeletal deposition of calcium and phosphate (Table 1). In some, mineral is precipitated as amorphous calcium phosphate or as crystals of hydroxyapatite; in others, osseous tissue is formed. The pathogenesis of ectopic mineralization is generally attributed to one of three mechanisms (Table 1). First, a supranormal “calcium-phosphate solu...

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Unusual ganglioglioma with extensive calcification and ossification.

Ganglioglioma is a slow-growing relatively low-grade mixed glioneuronal tumor with most cases corresponding to the WHO Grade I category. It frequently presents with seizures. The temporal lobe is the most common location followed by frontal, parietal, and occipital lobes. These generally behave in a benign fashion and have a favorable prognosis. We describe a case of a 24-year-old male presenti...

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Intracerebral metaplastic meningioma with prominent ossification and extensive calcification

We present a patient (male 26 years) with a short history of recurrent seizures induced by a largely intracerebrally located frontal lobe meningioma. The tumor displayed a heretofore unpublished combination of extensive metaplastic bone formation and prominent non-psammomatous calcifications with focal chicken-wire pattern.

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Primary Cervical Leiomyoma with Remarkable Calcification and Ossification

We encountered a patient with primary cervical leiomyoma with remarkable calcification and ossification. A 68-year-old man presenting with induration and swelling of the left submandibular region was found to have nodular lesions with calcifications in the left submandibular region and the upper mediastinum on CT. Fine needle aspiration biopsies (FNAB) of the left submandibular lesion revealed ...

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Histology of epiphyseal cartilage calcification and endochondral ossification.

Cartilage calcification is carried out by chondrocytes as they hypertrophy and begin to secrete matrix vesicles. Calcification initiates when calcium phosphates appear inside these matrix vesicles, forming hydroxyapatite crystals that eventually break through the membrane to form calcifying globules, as in bone calcification. However, the extracellular environment in cartilage is different from...

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ژورنال

عنوان ژورنال: Archives of Internal Medicine

سال: 1911

ISSN: 0003-9926

DOI: 10.1001/archinte.1911.00060060003001